Selected Publications (*co-first authorship; #co-corresponding/senior authorship)
Mikolajewicz, N., Gacesa, R., Aguilera-Uribe, M., Brown, K.R., Moffat, J.#, and Han, H.# (2022). Multi-level cellular and functional annotation of single-cell transcriptomes using scPipeline. Commun Biol, 5, 1142.
Tatari, N.*, Khan, S.*, Livingstone, J.*, Zhai, K., Mckenna, D., Ignatchenko, V., Chokshi, C., Gwynne, W.D., Singh, M., Revill, S., Mikolajewicz, N., Zhu, C., Chan, J., Hawkins, C., Lu, J.Q., Provias, J.P., Ask, K., Morrissy, S., Brown, S., Weiss, T., Weller, M., Han, H., Greenspoon, J.N., Moffat, J., Venugopal, C., Boutros, P.C.#, Singh, S.K.#, Kislinger, T.# (2022). The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers. Acta Neuropathol, 144, 1127-1142.
Qazi, M.A., Salim, S.K., Brown, K.R., Mikolajewicz, N., Savage, N., Han, H., Subapanditha, M.K., Bakhshinyan, D., Nixon, A., Vora, P., Desmond, K., Chokshi, C., Singh, M., Khoo, A., Macklin, A., Khan, S., Tatari, N., Winegarden, N., Richards, L., Pugh, T., Bock, N., Mansouri, A., Venugopal, C., Kislinger, T., Goyal, S., Moffat, J.#, and Singh, S.K.# (2022). Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma. Cell Reports, 40, 111420.
Han, H.*#, Best, A.J.*, Braunschweig, U.*, Mikolajewicz, N., Li, J., Roth, J., Chowdhury, F., Mantica, F., Nabeel-Shah, S., Parada, G., Brown, K.R., O’Hanlon, D., Wei, J., Yao, Y., Zid, A. A., Comsa, E., Jen, M., Wang, J., Datti, A., Gonatopoulos-Pournatzis, T., Weatheritt, R.J., Greenblatt, J.F., Wrana, J.L., Irimia, M., Gingras, A. C., Moffat, J.#, and Blencowe, B.J.# (2022). Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis. Molecular Cell, 82(16), 2982-2999.e14.
Seyfrid M.*, Maich W.T.*, Shaikh M.V., Tatari, N., Upreti, D., Piyasena, D., Subapanditha, M., Savage, N., McKenna, D., Mikolajewicz, N., Han, H., Chokshi, C., Kuhlmann, L., Khoo, A., Salim, S.K., Bassey-Archibong, B., Gwynne, W.D., Brown, K., Murtaza, N., Bakhshinyan, D., Vora, P., Venugopal, C., Kislinger, T., Moffat, J., and Singh, S.K. (2022). CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment. J Immunother Cancer, 10.
Aynaud, M. M.*, Hernandez, J. J.*, Barutcu, S.*, Braunschweig, U., Chan, K., Pearson, J. D., Trcka, D., Prosser, S. L., Kim, J., Barrios-Rodiles, M., Jen, M., Song, S., Shen, J., Bruce, C., Hazlett, B., Poutanen, S., Attisano, L., Bremner, R., Blencowe, B. J., Mazzulli, T., Han, H., Pelletier, L.# and Wrana, J. L.# (2021). A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2. Nature communications, 12, 1405.
Lawson, K. A.*, Sousa, C. M.*, Zhang, X., Kim, E., Akthar, R., Caumanns, J. J., Yao, Y., Mikolajewicz, N., Ross, C., Brown, K. R., Zid, A. A., Fan, Z. P., Hui, S., Krall, J. A., Simons, D. M., Slater, C. J., De Jesus, V., Tang, L., Singh, R., Goldford, J. E., Martin, S., Huang, Q., Francis, E. A., Habsid, A., Climie, R., Tieu, D., Wei, J., Li, R., Tong, A. H. Y., Aregger, M., Chan, K. S., Han, H., Wang, X., Mero, P., Brumell, J. H., Finelli, A., Ailles, L., Bader, G., Smolen, G. A., Kingsbury, G. A., Hart, T., Kung, C. and Moffat, J. (2020). Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Nature, 586, 120-126.
Mair, B.*, Tomic, J.*, Masud, S.N.*, Tonge, P., Weiss, A., Usaj M., Tong, A., Kwan, J., Brown, K.R., Titus, E., Atkins, M., Chan, K., Munsie, L., Habsid, A., Han, H., Kennedy, M., Cohen, B., Keller, G., and Moffat, J. (2019). Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Reports, 27, 599-615 e512.
Gonatopoulos-Pournatzis, T. *#, Wu, M.*, Braunschweig, U.*, Roth, J., Han, H., Best, A.J., Raj, B., Aregger, M., O’Hanlon, D., Ellis, J.D., Calarco, J. A., Moffat, J., Gingras, A. C. and Blencowe, B. J.# (2018). Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons. Molecular Cell, 72(3), 510-524.e12.
Han, H.*, Braunschweig, U.*, Gonatopoulos-Pournatzis, T., Weatheritt, R.J., Hirsch, C.L., Ha, K.C.H., Radovani, E., Nabeel-Shah, S., Sterne-Weiler, T., Wang, J., O’Hanlon, D., Pan, Q., Ray, D., Zheng, H., Vizeacoumar, F., Datti, A., Magomedova, L., Cummins, C.L., Hughes, T.R., Greenblatt, J.F., Wrana, J.L., Moffat, J., and Blencowe, B.J. (2017). Multilayered control of alternative splicing regulatory networks by transcription factors. Molecular Cell, 65(3), 539-553.e7.
Hirsch, C.L.*, Coban Akdemir, Z.*, Wang, L., Jayakumaran, G., Trcka, D., Weiss, A., Hernandez, J.J., Pan, Q., Han, H., Xu, X., Xia, Z., Salinger, A. P., Wilson, M., Vizeacoumar, F., Datti, A., Li, W., Cooney, A. J., Barton, M. C., Blencowe, B. J., Wrana, J. L.#, Dent, S. Y#. (2015). Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming. Genes & development, 29(8), 803-816.
Han, H.*, Irimia, M.*, Ross, P.J., Sung, H-K., Alipanahi, B., David, L., Golipour, A., Gabut, M., Michael, I.P., Nachman, E., Wang, E., Trcka, D., Thompson, T., O’Hanlon, D., Slobodeniuc, V., Barbosa-Morais, N.L., Burge, C.B., Moffat, J., Frey, B.J., Nagy, A., Ellis, J., Wrana, J.L. and Blencowe, B.J. (2013). MBNL proteins repress ES-cell-specific alternative splicing and reprogramming. Nature, 498(7453), 241-245.
Han, H., Nutiu, R., Moffat, J., and Blencowe, B.J. (2011) SnapShot: High-Throughput Sequencing Applications. Cell, 146(6), 1044-1044.e2.